Renowned faculty discuss the diagnosis of prediabetes and diabetes, including atypical forms of diabetes in adults. This course reviews the role of lifestyle interventions as well as appropriate indications and practical use of weight loss medications. The growing role of diabetes technology will be addressed as well as the risks and benefits of new insulin and noninsulin pharmacologic therapies, diabetes medications, cholesterol-lowering agents, and blood pressure control to reduce cardiometabolic risk.